Recommended use of palmitoylethanolamide

General palmitoylethanolamide dosing guidelines are as follows:

  • Initial dose: 1200 mg per day, with or without food, for the first 6 weeks.
  • Maintenance dose: 600 mg per day, with or without food.

A minimum dose of 20 mg per kg of body weight and maximum dose of 100 mg per kg of body weight can be used for a more individualized approach.

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