Independent clinical research supports OptiPEA® as natural ingredient for pain

Medical University of Graz, Austria

Leader in Quality and Innovation

OptiPEA® is a premium brand for palmitoylethanolamide worldwide. When it comes to manufacturing palmitoylethanolamide we have adopted and work in accordance with EU GMP standards. We only use high quality raw materials, novel process engineering and highly-sensitive full spectrum chemical analysis for research and quality assurance of our products.

The same stringent requirements as used in pharmaceutical manufacturing are implemented in the manufacturing process for OptiPEA®. All the steps are monitored continuously, and each production phase is documented in great detail.
OptiPEA® is produced in Europe in a state-of-the-art production facility by a team of PhD chemists. It is located in The Netherlands and has received EU GMP certification. OptiPEA® represents safety, reliability and quality.

Palmitoylethanolamide the most exciting nutraceutical you never heard of

Palmitoylethanolamide (PEA) is an effective solution for the management of chronic and neuropathic pain. Supported by more than 700 scientific articles, 60 medical indications for use, and 60 years of research, PEA is a natural compound that delivers compelling pain relief benefits. It is now readily available as the branded ingredient “OptiPEA®”.

Available OptiPEA® products

Standard Powder Palmitoylethanolamide

A fine particle size OptiPEA® powder with >99% PEA.

Water Dispersible Palmitoylethanolamide

A water dispersible version of OptiPEA® with a 90% PEA load.

Liposomal Palmitoylethanolamide

A liposomal version of OptiPEA® currently in redevelopment.


The oxazoline version of OptiPEA®, also known as PEA-OXA.

Science, Quality and Health


Palmitoylethanolamide (PEA) is a bioactive functional lipid that belongs to a class of molecules known as fatty acid amides. PEA is a naturally occurring compound that dates back hundreds of millions of years up the evolutionary path and is found in plant and animal cells. PEA has anti-inflammatory as well as pain-relieving properties. It acts as a protective and repairing molecule supporting the self-healing ability of the body.

Pure palmitoylethanolamide

By using highly sensitive methods of analysis we are able to characterize the complete composition of our raw material. Our PhD chemists know our PEA in detail and are very meticulous and strict when it comes to quality control, product release and product analyses. OptiPEA® has a consistent and high purity. The fine powder has a crystalline structure which makes it suitable for different applications.

Unique health benefits

PEA has often been described as a pleiotropic compound. It’s a “magic shotgun” capable of modulating numerous complex systems by hitting different important cellular targets simultaneously. Oral supplementation with PEA is an interesting alternative or worthwhile complementary strategy in the treatment of a large number of disease states, especially chronic pain, inflammation and de-generative diseases.